Editorial journal cover design
Since the beginning of the COVID-19 pandemic, there is an increasing need for fast and reliable viral diagnostic testing. Synthetic biologists designed a freeze-dried biomolecular platform that contains gene-circuit-based sensors to detect the presence of viruses. The technique has been adapted into glucose meters to create portable and fast diagnostic testing that doesn’t require a highly-trained technician. It only needs a droplet of viral sample to revitalize gene sensors and trigger a visible detection signal. This 3D visualization was created to depict this new biotechnology, and to attract audiences in this field of research.
Maya, Arnold renderer, Photoshop
Final presentation format
Editorial journal cover
The general public
Ideation and Thumbnails
After getting familiar with the topic and the specific research through the papers published by the Pardee Lab, several thumbnails are drafted up to visualize the technique.
Pardee, K., Green, A. A., Takahashi, M. K., Braff, D., Lambert, G., Lee, J. W., Ferrante, T., Ma, D., Donghia, N., Fan, M., Daringer, N. M., Bosch, I., Dudley, D. M., O’Connor, D. H., Gehrke, L., & Collins, J. J. (2016). Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components. Cell, 165(5), 1255–1266. https://doi.org/10.1016/j.cell.2016.04.059
Amalfitano, E., Karlikow, M., Norouzi, M., Jaenes, K., Cicek, S., Masum, F., Sadat Mousavi, P., Guo, Y., Tang, L., Sydor, A., Ma, D., Pearson, J. D., Trcka, D., Pinette, M., Ambagala, A., Babiuk, S., Pickering, B., Wrana, J., Bremner, R., … Pardee, K. (2021). A glucose meter interface for point-of-care gene circuit-based diagnostics. Nature Communications, 12(1), 724. https://doi.org/10.1038/s41467-020-20639-6
Yong, E. (2016, October 12). A New Way to Transport Vaccines and Detect Zika and Ebola. The Atlantic. https://www.theatlantic.com/science/archive/2016/10/to-make-vaccines-anywhere-just-add-water/503525/
U of T researchers present “lab in a box” for COVID-19 testing in online webinar | Leslie Dan Faculty of Pharmacy, University of Toronto. (2020). UofT LDFP. https://www.pharmacy.utoronto.ca/news-announcements/u-t-researchers-present-lab-box-covid-19-testing-online-webinar
The Scientist Creative Services Team. (2020, September 29). Combating COVID-19 with Cell-Free Expression. The Scientist Magazine®. https://www.the-scientist.com/the-marketplace/combating-covid-19-with-cell-free-expression-67840
Hoftyzer, E. H. (2021). PHARMACEUTICAL SCIENTISTS ADAPT GLUCOSE METER TO DIAGNOSE DISEASE. University of Toronto | Leslie Dan Faculty of Pharmacy. https://www.pharmacy.utoronto.ca/news-announcements/pharmaceutical-scientists-adapt-glucose-meter-diagnose-disease